Symbol
Name
ID

Apc
APC, WNT signaling pathway regulator
MGI:88039

Phenotype annotations related to nervous system

Darker colors indicate more annotations

Human Phenotypes

Cerebellar hemorrhage

Anorexia

Small intestine carcinoid

Cerebellar calcifications

Astrocytoma

Abnormal cranial nerve morphology

Hydrocephalus

Cerebellar cyst

Spinal cord tumor

Medulloblastoma

Cerebellar medulloblastoma

Neuroblastoma

Ataxia

Cerebellar ataxia associated with quadrupedal gait

Dysmetria

Progressive cerebellar ataxia

Intention tremor

Increased intracranial pressure

Irritability

Lethargy

Cognitive impairment

Abnormal brain FDG positron emission tomography

Headache

Global developmental delay

Disease(s) Associated with APC

familial adenomatous polyposis 1

medulloblastoma

pancreatic cancer

Mouse Phenotypes		abnormal neural tube morphology	abnormal floor plate morphology	abnormal brain development	abnormal hindbrain development	absent midbrain	absent forebrain
Availability	Mouse Genotype	abnormal neural tube morphology	abnormal floor plate morphology	abnormal brain development	abnormal hindbrain development	absent midbrain	absent forebrain
	Apc^tm3Mmt/Apc^tm3Mmt
	Apc^Min/Apc^tm1Tno
	Apc^tm1.1Tno/Apc^tm1Tno

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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